Sepsis is the international term used to characterize a generalized inflammatory response associated with a serious infection, a term that was coined in 1837 by the French physician Pierre Piorry, from the Greek words sêptikós (putrefaction), and haîma (blood). It refers to the presence of bacteria or viruses in the blood. Sepsis affects weakened individuals or newborns or the elderly, but above all it can affect people with no previous illness.

Globally, an estimated 13.7 million(Lancet, 2019) people die annually from sepsis. Projections into the future call for a doubling of the number of cases within fifty years, due to the aging population.